Program draft

Sunday (7 July 2024)

15:00Registration
17:00Opening Ceremony
Opening keynote presentations
19:00Welcome reception

Monday (8 July 2024)

optional commercial Breakfast/industry presentation
Plenary lecture
8:30-9:00

Parallel Session 1.
9:10-10:40

Novel structural insights and functions of cytochromes P450

Parallel Session 2.
9:10-10:40

Transcriptional and signaling-based regulation of drug metabolism

10:40 -11:10
Coffee break (30 min)

Parallel Session 3.
11:10-12:40

Mechanisms and dynamics of P450 and other xenobiotic-metabolizing enzymes

Parallel Session 4.
11:10-12:40

Nuclear Xenobiotic Receptors: PXR and CAR in metabolism and diseases

Lunch (12:40-13:40)

Poster presentation

Plenary lecture
13:40-14:10

Parallel Session 5.
14:10-15:40

CYPs in endogenous metabolism of lipids and steroids

Parallel Session 6.
14:10-15:40

Drug metabolizing enzymes, transporters, and nuclear receptors as therapeutic targets

15:40 - 16:10
Coffee break (30 min)

Parallel Session 7.
16:10- 17:40

Structure and functions of non-cytochrome P450 enzymes and phase II conjugation enzymes in drug metabolism

Parallel Session 8.
16:10- 17:40

Importance of ncRNAs and lncRNAs in metabolism regulation and liver diseases

19:00
Concert / mixer

Tuesday (9 July 2024)

optional commercial breakfast
Plenary lecture
8:30-9:00

Parallel Session 9.
9:10-10:40

Pharmacogenomics of drug-metabolizing enzymes: clinical relevance and ethnic diversity

Parallel Session 10.
9:10-10:40

Novel animal models to predict drug metabolism and toxicity

10:40 -11:10
Coffee break (30 min)

Parallel Session 11.
11:10-12:40

Biomarkers for prediction of drug metabolism and toxicity

Parallel Session 12.
11:10-12:40

3D experimental models and organ-on-chips in drug metabolism

Lunch (12:40-13:40)

Poster presentation/industry presentation

Plenary lecture
13:40-14:10

Parallel Session 13.
14:10-15:40

Inflammatory regulation of cytochrome P450 enzymes and COVID-19

Parallel Session 14.
14:10-15:40

Omics and single-cell-based technologies in the study of drug metabolism

15:40 -16:10
Coffee break (30 min)

Parallel Session 15.
16:10-17:40

Interactions of microbiome on drug metabolism

Parallel Session 16.
16:10-17:40

Oligonucleotide and peptide ADME

19:00

Dinner

Wednesday (10 July 2024)

optional commercial breakfast
Plenary lecture
8:30-9:00

Parallel Session 17.
9:10-10:40

In vitro and in silico systems for prediction of drug metabolism and toxicity/ In vitro to in vivo extrapolation (IVIVE) in drug development

Parallel Session 18.
9:10-10:40

Drug transporters and their impact on drug metabolism and disposition

10:40 -11:10
Coffee break (30 min)

Parallel Session 19.
11:10-12:40

In silico and PBPK(D) modeling of drug metabolism / Quantitative systems pharmacology (QSP)

Parallel Session 20.
11:10-12:40

Intestinal and extrahepatic metabolizing enzymes in bioavailability and disposition

13:00
Closing Ceremony / Awards

Visit to Prague Castle